Posted on November 11, 2007 by Trevor Butterworth
Trevor Butterworth
The current issue of Biocentury, a trade publication that covers the pharmaceutical industry, should be essential and chastening reading for the journalists, editors and politicians who helped turn a limited, problematic study on the risks of the diabetes drug rosliglitazone (brand name Avandia) into a major international health scare.
In a comprehensive report on the [...]
Filed under: Avandia, Diabetes, Endocrinology, Food and Drug Administration, Meta Analysis, Statistical Analysis | Tagged: Annals of Internal Medicine, Biocentury, David Graham, HbA1c, Medstar Research Institute, New England Journal of Medicine, Steve Nissen, Steve Usdin | 1 Comment »
Posted on November 9, 2007 by Trevor Butterworth
Trevor Butterworth, Huffington Post
Take several critics of the way the FDA ensures the safety of drugs, rush a flawed study into print, characterize the results as catastrophic, rope in drug regulation warriors on Capitol Hill, rant about the evils of Big Pharma, talk to a credulous, statistically-illiterate media, and voila - you have Vioxx II, [...]
Filed under: Avandia, Diabetes, Endocrinology, Food and Drug Administration, Meta Analysis, STATS on Huffington Post | Tagged: Avandia, heart attack, New England Journal of Medicine, Steve Nissen | No Comments »
Posted on November 9, 2007 by Trevor Butterworth
Trevor Butterworth
The line between the New York Times editorial page, which has been highly critical of the FDA’s handling of the potential risk from the diabetes drug Avandia, and the health news pages appears to have disappeared in the Times’ coverage of the forthcoming FDA hearings on the drug… more
Originally published July 27, 2007
Filed under: Avandia, Diabetes, Endocrinology, Food and Drug Administration, Meta Analysis, Statistical Analysis | Tagged: , Bruce Psaty, Nature Clinical Practice, New England Journal of Medicine, New York Times, Steve Nissen, The Lancet | No Comments »
Posted on November 9, 2007 by Trevor Butterworth
Trevor Butterworth, Huffington Post
As another major scientific journal criticizes the methodology behind a study in the New England Journal of Medicine (NEJM) that prompted a nationwide panic over a popular diabetes drug, it turns out that the doctor who authored the study, Steven Nissen MD, delivered a blistering attack on those very methods seven years [...]
Filed under: Avandia, Diabetes, Meta Analysis, Pharmaceuticals, Statistical Analysis, risk analysis | Tagged: Avandia, heart attack, New England Journal of Medicine, Steve Nissen | No Comments »